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MMP27  Protein, Antibody, ELISA Kit, cDNA Clone

MMP27 Related Area

MMP27 Related Pathways

    MMP27 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    MMP27 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    MMP27 Summary & Protein Information

    MMP27 Background

    Cofactor: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; ; Note=Binds 4 Ca(2+) ions per subunit. {ECO:0000250};; Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; ; Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
    Domain: The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    Subcellular location: Endoplasmic reticulum membrane; Peripheral membrane protein {ECO:0000269|PubMed:24548619}. Note=Retained in the endoplasmic reticulum. {ECO:0000269|PubMed:24548619}.
    Tissue specificity: Expressed in B-cells (PubMed:14506071). Expressed in a subset of endometrial macrophages related to menstruation and in ovarian and peritoneal endometriotic lesions (at protein level)(PubMed:24810263). {ECO:0000269|PubMed:14506071, ECO:0000269|PubMed:24810263}.
    Post-translational: N-glycosylated. {ECO:0000269|PubMed:24548619}.
    Sequence similarity: Belongs to the peptidase M10A family. {ECO:0000305}.; Contains 4 hemopexin repeats. {ECO:0000305}.
    General information above from UniProt

    MMP27 Alternative Name

    MMP-27, [homo-sapiens]
    Gm180, [mus-musculus]

    MMP27 Related Studies

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