cDNA Clones

Sino Biological Inc. provides scientists worldwide with multiple forms of cDNA clones including expression-ready cDNA ORF clones, lentivirus cDNA ORF clones, and cDNA Clone in cloning vectors. All gene products were verified by full-length sequencing to ensure high-quality cDNA clones. Sino Biological has always been committed to providing customers with high quality products and services.

See All cDNA Clones >>>

Advantages of cDNA Clones

Gene Bank: 11,000+ molecules, 400,000+ cDNA clones, most are ready to ship
Multiple Species: Human、Mouse、Rat、Rabbit、Rhesus、Cynomolgus、Canine、Ferret、zebra fish、Virus...
Multiple Tags: N-terminal or C-terminal Myc、HA、FLAG、His、GFPSpark? and OFPSpark?
Influenza Virus Gene Bank: 60 subtypes, 160 strains, including H7N9, H5N1 and other popular strains; and genes of nearly 40 kinds of viruses such as MERS COV, HCV, RSV, HCov...
Full length sequence confirmed: Each gene product is verified by full-length sequencing; ~100% sequence accuracy
Customized service: Meet customer's needs

Types of cDNA Clone Products

cDNA Clone in Cloning Vector

Sequence Verification	Full length sequence confirmed
Expression Validated	No
Expression Host	None
Vectors	pMD18-T/pMD19-T/pGEM-T/pUC19
Tags	None
Application	PCR template; quantitative PCR template; study of gene function
Features	Ultra low-cost

Expression-ready ORF Clone

Sequence Verification	Full length sequence confirmed
Expression Validated	Yes
Expression Host	Mammalian cell
Vectors	pCMV/pCMV3-Series
Tags	untagged、N-/C-Flag/HA/His/Myc/GFPSpark?/OFPSpark?
Application	Protein overexpression; protein detection and purification; cell localization; stable strain construction
Features	Expression validated, quality assurance

Lentiviral ORF Clone

Sequence Verification	Full length sequence confirmed
Expression Validated	Yes
Expression Host	Mammalian cell
Vectors	pLV-Series
Tags	untagged、N-/C-Flag/HA/His/Myc/GFPSpark?/OFPSpark?
Application	Packaging lentivirus; protein overexpression; stable strain construction
Features	Transfection of dividing and non-dividing cells, primary cells, stem cells and other difficult-to-transfect cells

Expression-ready ORF Clone: Expression Validated

Human PTPN1, N-Flag
(HG10304-NF)

Human IDH1, N-GFPSpark?
(HG12055-ANG)

Human SIRT6, C-GFPSpark?
(HG12156-ACG)

H7N9-NP, C-Flag
(VG40110-CF)

Human PKM2, C-OFPSpark?
(HG11430-ACR)

Human MTOR, C-OFPSpark?
(HG11508-ACR)

Featured cDNA Clones：Organelle Marker Plasmid

Sino Biological provides a collection of fluorescent fusion proteins that are targeted to various organelles or subcellular structures. The fluorescent fusion protein is introduced using a simple transfection step, after 48h, you can take the beautiful images directly by fluorescence microscopy.

GFPSpark? or OFPSpark? fluorescent colors for choice	Easy labeling of cell compartments and proteins
Perfect for study of localization and trafficking	No antibody or chemical treatment required

cDNA Clone Quality Control Standards

cDNA clones are controlled by strict quality control and Sino Biological only provides you with high quality plasmids:
a) One plasmid was sequenced twice to ensure sequence accuracy
b) UV and electrophoresis：A260/A280 = 1.8~2.0, guarantee plasmid purity
c) PCR identification：Identify gene size and exclude plasmid contamination

cDNA Clone Product Citations(Partial)

Organization	Molecule	Catalog No.	Reference Citations	Published Journals
Georgia Regents University, etc.	ISL1	HG13122-G	DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis	Nat Commun
Swiss Federal Institute of Technology	IL9	MG51302-G	Glycosylation profiles determine extravasation and disease-targeting properties of armed antibodies	Proc. Natl. Acad. Sci. U.S.A.
Cincinnati Children's Hospital Medical Center,etc.	SMAD3	MG50991-UT	TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium	Development
INRS-Institut-Armand-Frappier	BMP-4	HG10609-CF	Bone morphogenetic protein 4 (BMP-4) and epidermal growth factor (EGF) inhibit metalloproteinase-9 (MMP-9) expression in cancer cells	Oncoscience
Jinling Hospital, School of Medicine, Nanjing University	GSK3b	HG10044-M	MicroRNA-451 induces epithelial–mesenchymal transition in docetaxel-resistant lung adenocarcinoma cells by targeting proto-oncogene c-Myc	European Journal of Cancer
The Johns Hopkins University,etc.	furin	HG10141-M	Preparation and properties of a papillomavirus infectious intermediate and its utility for neutralization studies	Virology