FLT4 (Protein | Antibody | cDNA Clone | ELISA Kit)

All FLT4 reagents are produced in house and quality controlled, including 10 FLT4 Antibody, 2 FLT4 ELISA, 29 FLT4 Gene, 4 FLT4 Lysate, 4 FLT4 Protein, 2 FLT4 qPCR. All FLT4 reagents are ready to use.

More Product Popular With Customers

FLT4 Background

Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR3 signaling pathway may provide a target for antilymphangiogenic therapy in prostate cancer, breast cancer, gastric cancer, lung cancer, non-small cell lung cancer (NSCLC), and so on.

FLT4 References

  • Shushanov S, et al. (2000)VEGFc and VEGFR3 expression in human thyroid pathologies. Int J Cancer.86(1): 47-52.
  • Iljin K, et al. (2001) VEGFR3 gene structure, regulatory region, and sequence polymorphisms. FASEB J. 15(6): 1028-36.
  • Liu XE, et al. (2004) Expression and significance of VEGF-C and FLT-4 in gastric cancer. World J Gastroenterol. 10(3): 352-5.
  • Stearns ME, et al. (2004) Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Lab Invest. 84(6): 785-95.
彩票大奖得主捐赠 二四六好彩免费资料 配资平台跑路了,投资人如何举报立案 青海11选5玩法 意大利pk10技巧 龙湖配资 2020香港正版欲钱料全选 广东福彩36选7预测分析 广西快3下载 基金配资合法性 三分赛车技巧图解