LIF (Protein | Antibody | cDNA Clone | ELISA Kit)

All LIF reagents are produced in house and quality controlled, including 5 LIF Antibody, 39 LIF Gene, 3 LIF Lysate, 5 LIF Protein, 2 LIF qPCR. All LIF reagents are ready to use.

More Product Popular With Customers

LIF Background

Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It’s involved in growth promotion and cell differentiation of different types of target cells, influence on bone metabolism, cachexia, neural development, embryogenesis and inflammation. LIF has potent proinflammatory property, being the inducer of the acute phase protein synthesis and affecting the cell recruitment into the area of damage or inflammation. LIF is also one of the cytokines that are capable to regulate the differentiation of embryonic stem cells, hematopoietic and neuronal cells. LIF binds to the specific LIF receptor (LIFR-α) which forms a heterodimer with a specific subunit common to all members of that family of receptors, the GP13 signal transducing subunit. This leads to activation of the JAK/STAT and MAPK cascades. Due to its polyfunctional activities, LIF is involved in the pathogenic events and development of many diseases of various origin.

LIF References

  • Salas EM, et al. (2011) LIF, a Novel STAT5-Regulated Gene, Is Aberrantly Expressed in Myeloproliferative Neoplasms. Genes Cancer. 2 (5): 593-6.
  • Chodorowska G, et al. (2004) Leukemia inhibitory factor (LIF) and its biological activity. Ann Univ Mariae Curie Sklodowska Med. 59 (2): 189-93.
  • Garcia-Campana AM, et al. (2007) LIF detection of peptides and proteins in CE. Electrophoresis. 28 (1-2): 208-32.
彩票大奖得主捐赠 吉林快3一定牛走势 江苏11选5复式计算器 河南泳坛夺金500期 上海股票期货配资公司 北京pk10走势图北京pk10历史开奖记录 四肖八码中特期期准精选 股票期权的平台 四川快乐十二电视版走势图 三期内必开一期王中王 江西11选5走势