Anti-Lipocalin-2 / LCN2 Antibody


Anti-Lipocalin-2 / LCN2 Antibody (Rabbit Polyclonal antibody) General Information

Product name
Anti-Lipocalin-2 / LCN2 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human Lipocalin-2 / LCN2
Recombinant Human LCN2 protein (Catalog#10222-H08H)
Produced in rabbits immunized with purified, recombinant Human Lipocalin-2 (rh Lipocalin-2; Catalog#10222-H08H; NP_005555.2; Met 1-Gly 198). LCN2 specific IgG was purified by human LCN2 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Lipocalin-2 / LCN2 Antibody (Rabbit Polyclonal antibody) Validated Applications

Application Dilution
ELISA 1:1000-1:2000
IHC-P 1:500-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Lipocalin-2 / LCN2 Antibody (Rabbit Polyclonal antibody) Images

Immunochemical staining of human LCN2 in human spleen with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).

Anti-Lipocalin-2 / LCN2 Antibody: Alternative Names

Anti-24p3 Antibody; Anti-Lipocalin-2 Antibody; Anti-MSFI Antibody; Anti-NGAL Antibody; Anti-p25 Antibody

Lipocalin-2 / LCN2 Background Information

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells, like kidney tubular cells, may produce NGAL in response to various insults. This protein is released from injured tubular cells after various damaging stimuli, is already known by nephrologists as one of the most promising biomarkers of incoming Acute Kidney Injury (AKI). Recent evidence also suggests its role as a biomarker in a variety of other renal and non-renal conditions. Moreover, recent studies seem to suggest a potential involvement of this factor also in the genesis and progression of chronic kidney diseases. NGAL is the first known mammalian protein which specifically binds organic molecules called siderophores, which are high-affinity iron chelators. NGAL, first known as an antibacterial factor of natural immunity, and an acute phase protein, is currently one of the most interesting and enigmatic proteins involved in the process of tumor development. acting as an intracellular iron carrier and protecting MMP9 from proteolytic degradation, NGAL has a clear pro-tumoral effect, as has already been observed in different tumors (e.g. breast, stomach, oesophagus, brain) in humans. In thyroid carcinomas, NGAL is strongly induced by NF-kB, an important factor involved both in tumor growth and in the link between chronic inflammation and neoplastic development. Thus, Lipocalin-2 (LCN2/NGAL) has been implicated in a variety of processes including cell differentiation, proliferation, survival and morphogenesis.
Full Name
lipocalin 2
  • Schmidt-Ott KM, et al. (2006) Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr Opin Nephrol Hypertens. 15(4): 442-9.
  • Bolignano D, et al. (2010) Neutrophil gelatinase-associated lipocalin (NGAL) in human neoplasias: a new protein enters the scene. Cancer Lett. 288(1): 10-6.
  • Soni SS, et al. (2010) NGAL: a biomarker of acute kidney injury and other systemic conditions. Int Urol Nephrol. 42(1): 141-50.
  • Bolignano D, et al. (2010) From kidney to cardiovascular diseases: NGAL as a biomarker beyond the confines of nephrology. Eur J Clin Invest. 40(3): 273-6.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

Add to Cart Successfully Add to Cart Failed Shopping cart is being updated, please wait
彩票大奖得主捐赠 一分彩精准计划软件 北京pk10破解软件下载 幸运农场玩法说明 吉林快3预测吉林快三推荐一定牛 腾讯分分彩害死人 股票的上证指数是什么 线上股票炒股配资 福建11选五预测任选5 职业炒股的人都孤僻 20选五走势图带连线