BMP-2 (Protein | Antibody | cDNA Clone | ELISA Kit)

All BMP-2 reagents are produced in house and quality controlled, including 6 BMP-2 Antibody, 2 BMP-2 ELISA, 52 BMP-2 Gene, 1 BMP-2 IP Kit, 1 BMP-2 Lysate, 3 BMP-2 Protein, 3 BMP-2 qPCR. All BMP-2 reagents are ready to use.

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BMP-2 Background

BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

BMP-2 References

  • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
  • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
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